"High-Precision Analysis of Genetic Variants, SNPs, and Mutations for Disease Research, Genotyping, Microbial Studies, and Precision Medicine with Advanced Next-Generation Sequencing and Bioinformatics Solutions."
Amplicon Sequencing is a targeted DNA sequencing technique that focuses on specific genomic regions of interest, providing high precision and accuracy in detecting genetic variants. This service uses polymerase chain reaction (PCR) to amplify desired regions, such as genes, SNPs, or mutations, followed by next-generation sequencing (NGS) for in-depth analysis. Ideal for applications like microbial community profiling, cancer genomics, hereditary disease research, and genotyping, amplicon sequencing offers a cost-effective and scalable solution. Advanced bioinformatics pipelines ensure accurate variant calling and comprehensive data interpretation. Our service delivers reliable, high-resolution insights, empowering researchers and clinicians in precision medicine and genetic research.
2 Types of Amplicon Sequencing Services
16S rRNA Gene Sequencing
This service is used for microbial community analysis, specifically targeting the 16S ribosomal RNA gene in bacteria. It enables the identification and characterization of microbiomes in environmental, clinical, or agricultural samples, aiding in the study of microbial diversity and disease-associated microbes.
Targeted Variant Sequencing
Focused on specific genetic variants, this service amplifies and sequences selected regions of the genome, such as exons, specific mutations, or known SNPs. It is used for applications like cancer mutation profiling, genotyping, and genetic disease diagnostics, providing high sensitivity and accuracy for variant detection.
Amplicon sequencing is a targeted approach for sequencing specific genomic regions of interest, offering high sensitivity and precision in variant detection. The process begins with sample collection, such as blood, tissue, or environmental samples, followed by DNA extraction. Once the DNA is isolated, the target regions, such as specific genes or mutations, are amplified using polymerase chain reaction (PCR). This process generates millions of copies of the selected DNA fragments, which are then prepared for sequencing.
The amplified DNA is sequenced using next-generation sequencing (NGS), producing high-resolution data. The raw sequencing reads are aligned to a reference genome and analyzed through bioinformatics pipelines to identify genetic variants, mutations, or microbial species present in the sample.
Finally, the results are interpreted to uncover insights into genetic variations, disease markers, or microbial diversity. Amplicon sequencing is widely used in cancer research, microbial profiling, genetic disease diagnostics, and precision medicine applications, providing detailed, actionable data.